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Knowledgebase : Symantec
Below you will find a link to the Microsoft explanation, and to some other work around for this issue. 452 4.3.1 Insufficient system resources - on relay of: mail from A reputable resolution can be found at the following URL:
ERROR: This domain name does not match domain registered in the license key file (, allowed domains:,localhost, please change the product path to match the domain under Admin CP > Settings > General Settings
This product will not work properly unless untill that value is changed.

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